Overview
Pyridoxal-5-Phosphate (P5P) is the active form of B6. It is the rate-limiting cofactor for the enzyme (GAD) that converts Glutamate (excitatory) into GABA (calming). Without it, you cannot produce the brake.
Health Goals Impacted 1
This item supports, tracks, or is required for the following health goals:
Required to make GABA.
The enzyme GAD65 converts Glutamate (anxiety) into GABA (calm). This enzyme is completely dependent on Vitamin B6. A deficiency here creates a bottleneck where you have plenty of fuel but no way to produce the calming neurotransmitter.
Magnesium cannot enter the cell efficiently without B6. They work in tandem; B6 builds the GABA neurotransmitter, while Magnesium allows the GABA receptor to function.