Overview
Gamma-Aminobutyric Acid (GABA) is the brain's main "chill" signal. While there is debate about crossing the blood-brain barrier, evidence suggests "PharmaGABA" (fermented) acts on the enteric nervous system (gut brain) to produce a calming effect.
Health Goals Impacted 1
This item supports, tracks, or is required for the following health goals:
Directly stimulates relaxation receptors.
GABA supplements bind to GABA-A receptors (the same targets as alcohol and benzos). This opens chloride channels in the neuron, making it harder for the neuron to "fire," thus physically slowing down the stress response.
While the "blood-brain barrier" debate exists, the Enteric Nervous System (gut brain) is rich in GABA receptors. Stimulating these receptors sends a calming signal up the Vagus Nerve to the brainstem, bypassing the BBB entirely.