📊 Metric

Lipoprotein(a)

The genetic heart risk factor

📖 Overview

Lp(a) is a specific type of LDL particle with a "sticky" tail. Levels are 90% genetic and do not respond well to diet or statins. High Lp(a) is a major independent risk factor for heart attacks and requires aggressive management of other risk factors.

🎯 Health Goals Impacted 1

This item supports, tracks, or is required for the following health goals:

Reduce LDL Cholesterol

📊 Tracks

The most important genetic marker for CVD.

Lp(a) is the "widowmaker" lipid due to its structure: it resembles plasminogen, meaning it promotes clotting (thrombosis) in addition to forming plaque. Because it is genetically determined, diet and exercise have little effect on levels.

Knowing your Lp(a) status helps determine how aggressively you need to lower your standard ApoB target to offset this unchangeable risk factor.

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